What Is 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4? Properties, Uses, and Buying Guide

2-Bromopyridine-5-carbaldehyde, identified by CAS 149806-06-4, is a brominated pyridine aldehyde used primarily as a synthetic building block in pharmaceutical, agrochemical, and specialty chemical research. Its molecule combines a pyridine nitrogen, a bromine substituent, and an aldehyde group, creating several useful points for further chemical transformation. The compound has the molecular formula C₆H₄BrNO and a calculated molecular weight of approximately 186.01 g/mol. We supply this type of pharmaceutical intermediate with documentation and packaging options matched to project requirements.

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Direct Definition and Chemical Identity

2-Bromopyridine-5-carbaldehyde is a heteroaromatic aldehyde in which the aldehyde group is positioned at the 5-position of a pyridine ring and bromine is positioned at the 2-position. The pyridine ring provides a nitrogen-containing aromatic framework, while the aldehyde group can participate in condensation and other carbon–carbon or carbon–heteroatom bond-forming reactions. The aryl bromide can also serve as a coupling handle in appropriately designed synthetic routes.

The compound should not be confused with other bromopyridine aldehyde isomers. Position isomerism can change reactivity, downstream regioselectivity, analytical behavior, and suitability for a particular intermediate route. For that reason, I recommend confirming both the CAS number and the structural name before ordering.

Core Functions and Synthetic Value

The main value of 2-Bromopyridine-5-carbaldehyde is its multifunctional structure. The aldehyde group may be used in reactions such as imine formation, reductive amination, oxime formation, and selected condensation processes, depending on the reaction design. The bromine substituent may support palladium-catalyzed or other cross-coupling strategies when the substrate, catalyst system, and process conditions are compatible.

The pyridine nitrogen can influence coordination, polarity, solubility, and the electronic behavior of the aromatic ring. These features make the compound useful when a development team needs to introduce a substituted pyridyl unit into a more complex molecule. Actual reaction performance depends on solvent, catalyst, temperature, stoichiometry, purification method, and the sensitivity of the target structure.

Why the Two Reactive Sites Matter

Having an aldehyde and an aryl bromide in the same molecule allows chemists to plan sequential or selective transformations. In some routes, the aldehyde is converted first and the bromide is retained for a later coupling step; in other routes, the order may be reversed. I recommend confirming chemoselectivity at laboratory scale before committing to a larger production quantity.

Potential Application Scenarios

2-Bromopyridine-5-carbaldehyde is commonly considered a research and development intermediate rather than a finished active ingredient. Pharmaceutical chemistry teams may evaluate it for the preparation of nitrogen-containing lead compounds and advanced intermediates. It may also be investigated in medicinal chemistry libraries where a substituted pyridine ring and aldehyde-derived functionality are required.

In agrochemical and specialty chemical development, the compound may serve as a precursor for heteroaromatic structures, ligand research, or other small-molecule synthesis programs. These applications should be treated as route-dependent possibilities rather than guaranteed end uses. The buyer should confirm regulatory status, intended use, and process suitability for the relevant market.

Types and Material Options Buyers May Request

For this product, “types” usually refer to supply specifications rather than fundamentally different chemical grades. A buyer may request research grade, synthesis grade, or a project-specific intermediate grade, with the precise requirements defined in the purchase specification. Common specification topics include assay or purity, water content, residual solvents, appearance, identification, and packaging.

We can discuss standard material and customized requirements according to the application. However, a specification such as 98% or 99% purity should be treated as a requested target unless it is confirmed by the current product specification and certificate of analysis. I do not recommend selecting a supplier based on a headline purity number alone.

Typical Documentation Package

For B2B purchasing, useful documents may include a specification sheet, certificate of analysis, safety data sheet, batch or lot information, and packing details. Additional documents may be available when required by the project and agreed before shipment. Document availability should be confirmed before placing an order, especially when the material will enter a regulated development process.

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Key Specifications and Handling Considerations

The most important identity controls are the CAS number, molecular formula, molecular weight, and analytical confirmation of the structure. Buyers commonly review chromatographic purity together with spectroscopic or other identification data. Because physical appearance, water content, and impurity profiles can vary by batch and manufacturing route, I recommend relying on the current batch documents rather than an unverified online description.

As an aromatic aldehyde and brominated heterocycle, the material should be handled according to its current SDS and the buyer’s laboratory or production safety procedures. Personnel should use suitable protective equipment, avoid unnecessary exposure, and control dust or vapor during weighing and processing. Storage conditions, light protection, inert-gas requirements, and shelf-life should be confirmed from the supplier’s instructions and the specific packaging configuration.

The product is intended for chemical synthesis and research use unless a different legal use has been specifically established. It should not be represented as a pharmaceutical ingredient, food ingredient, or approved treatment without the appropriate regulatory evaluation. Our team can help buyers identify the documentation needed for their intended application, but the final compliance assessment remains with the purchaser.

How to Select a Reliable Supply Specification

1. Confirm Identity Before Comparing Price

Start with CAS 149806-06-4, the full chemical name, formula, and structure. Ask whether the offered material is the correct 2-bromo-5-formyl pyridine isomer and request a representative analytical package. This step reduces the risk of receiving a similar but unsuitable bromopyridine aldehyde.

2. Match Purity to the Process

High-purity material may be appropriate for sensitive discovery chemistry or a route with limited purification capability, while a different specification may be acceptable for an earlier screening step. The correct target depends on impurity tolerance, reaction yield, downstream purification, and the cost of failure. We can review the intended route and help define a practical specification instead of recommending an unnecessarily restrictive one.

3. Review Packaging, Quantity, and Logistics

Confirm the requested quantity, container type, labeling, shipping classification, and delivery destination. A small laboratory order and a kilo-scale development order may require different packaging and documentation controls. Lead time should be quoted against the required specification and quantity, rather than assumed from a catalog listing.

4. Evaluate Supply Continuity

For development programs, buyers should ask about batch consistency, production scheduling, quality communication, and the possibility of repeat supply. A low initial price does not necessarily represent the lowest total procurement risk. We encourage customers to provide forecast quantities and target delivery windows so that production and logistics can be planned more responsibly.

Maison Chemical Supplier Support

At Maison Chemical, we support B2B buyers sourcing pharmaceutical intermediates and specialty chemical building blocks. For 2-Bromopyridine-5-carbaldehyde, we can discuss product identity, specification expectations, packaging, documentation, and shipment planning before quotation. Our approach is to clarify the technical and commercial requirements first, then provide a supply proposal suited to the project.

We can also help compare a standard specification with a customized requirement, provided the requested tests and acceptance criteria are clearly defined. If a buyer needs repeat batches, we recommend confirming the required purity range, analytical methods, pack size, and forecast schedule at the beginning of the project. This creates a clearer basis for quality review and future purchasing.

Key Takeaways

• 2-Bromopyridine-5-carbaldehyde is a multifunctional heteroaromatic intermediate with CAS 149806-06-4.
• Its molecular formula is C₆H₄BrNO, and its calculated molecular weight is approximately 186.01 g/mol.
• The aldehyde and aryl bromide provide complementary opportunities for further synthesis.
• Potential uses include pharmaceutical, agrochemical, specialty chemical, and medicinal chemistry development.
• Buyers should verify the isomer, current COA, SDS, purity requirement, packaging, lead time, and regulatory documentation.

Conclusion and Next Steps

In direct answer, 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 is a brominated pyridine aldehyde used as a versatile synthetic intermediate. Its aldehyde group and aryl bromide can support different transformation strategies, while the pyridine ring contributes a valuable nitrogen-containing aromatic framework. The best purchasing decision depends on the intended route, required purity, analytical controls, quantity, documentation, and delivery plan.

Before ordering, I recommend sending the supplier your target quantity, purity requirement, intended use, packaging preference, destination, and desired delivery date. Maison Chemical can then review the request and provide a practical quotation with available technical and shipping information. Contact our chemicals team to discuss your 2-Bromopyridine-5-carbaldehyde sourcing requirements and establish the next step for evaluation or supply.

The company is the world’s best 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4 supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.