4-Isopropylbenzeneboronic Acid CAS 16152-51-5: A Buyer’s Guide to Specifications, Applications, and Supplier Documentation

4-Isopropylbenzeneboronic acid, also called 4-isopropylphenylboronic acid, is an aryl boronic acid used primarily as a synthetic building block in pharmaceutical, agrochemical, and advanced organic chemistry projects. Its CAS Registry Number is 16152-51-5, and its commonly calculated molecular formula is C₉H₁₃BO₂, corresponding to a molecular weight of approximately 164.01 g/mol. I recommend evaluating this material by identity, assay, water content, appearance, packaging, documentation, and supply continuity rather than by price alone. Maison Chemical can support a structured quotation and documentation review based on your required grade, quantity, and application.

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Who This Guide Is For

This guide is intended for procurement teams, process chemists, research laboratories, pharmaceutical development groups, and distributors sourcing 4-isopropylbenzeneboronic acid. It is particularly useful when the buyer needs to compare several suppliers or convert a laboratory requirement into a repeatable purchasing specification. The guide also helps distinguish confirmed product data from information that must be verified in the supplier’s current technical documents.

I use a conservative approach because boronic acid products can differ in assay, residual solvents, water content, particle form, packaging, and analytical method. A catalog description may be sufficient for an early screening project, but a regulated or scale-up program normally requires a current Certificate of Analysis, Safety Data Sheet, specification sheet, and traceability information. The final acceptance criteria should always be agreed before purchase.

Basic Product Context

4-Isopropylbenzeneboronic acid contains an aryl boronic acid functional group and a para-isopropyl substituent on the benzene ring. In synthetic chemistry, the boronic acid group is commonly used as a coupling partner in carbon–carbon bond-forming reactions, especially Suzuki–Miyaura-type transformations. The isopropyl substituent can provide a defined hydrophobic and steric feature when the compound is incorporated into a research intermediate or target molecule.

The molecular weight of approximately 164.01 g/mol is useful for calculating molar quantities, reaction charges, and theoretical yields. For example, 1.00 g of material corresponds to approximately 6.10 mmol before correcting for assay and water content. This calculation is only a starting point; the actual weighed amount should be adjusted according to the supplier’s reported purity and the project’s analytical requirements.

For general chemical nomenclature and substance-information verification, I recommend checking the CAS number and product identity against reliable databases such as the National Library of Medicine PubChem database. PubChem is useful for cross-checking identifiers and calculated properties, but the supplier’s batch-specific CoA remains the appropriate source for release testing and lot acceptance.

Specifications and Material Options to Review

Identity and Composition

The first specification should confirm the product name, CAS number, molecular formula, molecular weight, and structural identity. For this material, the key identifier is CAS 16152-51-5, while the commonly associated formula and molecular weight are C₉H₁₃BO₂ and approximately 164.01 g/mol, respectively. I advise buyers to request confirmation of identity by an appropriate analytical technique, such as NMR, MS, or another method listed in the supplier’s specification.

Assay requirements should be defined before quotation. Research-grade procurement may accept a supplier’s standard assay specification, while process development or regulated applications may require a tighter internal limit, defined impurity controls, and a validated or clearly described analytical method. Do not assume that a listed purity of 95%, 98%, or another value applies to every available lot; ask for the current lot-specific result.

Physical and Handling Information

Appearance, physical form, color, and packaging can affect laboratory handling and quality inspection. A buyer may specify a visual requirement such as a solid material with no abnormal discoloration, but the exact appearance should follow the supplier’s approved specification rather than an informal catalog description. Melting point, solubility, and storage conditions should also be confirmed from the current SDS or technical data sheet because these values can depend on measurement method and material condition.

Water content deserves special attention because boronic acids may be sensitive to moisture-related changes during storage or handling. If water affects your reaction performance, request a Karl Fischer result or an agreed moisture limit, expressed in % or ppm. If the supplier does not routinely test moisture, the buyer should determine whether a special test is necessary before placing a production-oriented order.

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Matching the Material to Its Application

For medicinal chemistry and discovery research, the most important factors are usually confirmed identity, acceptable assay, practical pack size, and delivery speed. A small project may need only a few grams, while a route-development program may require repeated supply in quantities such as 10 g, 100 g, or 1 kg. I recommend confirming whether the same specification can be maintained across pack sizes before moving from screening to scale-up.

For Suzuki–Miyaura-related work, the buyer should discuss reaction sensitivity with the technical supplier. Catalyst system, base, solvent, temperature, reaction time, and substrate structure can all influence performance, so the boronic acid should not be treated as the only variable. A supplier can provide product documentation and, where available, analytical information, but the customer’s laboratory remains responsible for confirming suitability in the intended reaction.

For pharmaceutical or agrochemical intermediate development, buyers may need stronger control of trace impurities, residual solvents, inorganic residues, and change notification. The appropriate level of control depends on the stage of development and the customer’s quality system. A research material is not automatically suitable for a regulated manufacturing process simply because it has a high stated assay.

For custom synthesis or route support, the key question is whether the supplier can provide a stable specification, documented change control, and realistic capacity planning. I recommend identifying the expected annual demand, forecast horizon, preferred batch size, and required delivery window before requesting a long-term quotation. These details allow the supplier to evaluate whether standard stock, scheduled production, or a custom supply arrangement is most appropriate.

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A Practical Buyer Selection Framework

Step 1: Define the Technical Requirement

Start with the exact identity, CAS number, intended use, target quantity, minimum assay, and required documentation. State whether the material is for exploratory research, process development, distribution, or a later-stage manufacturing program. If the project has a maximum limit for water, metals, residual solvents, or related substances, include those requirements in the initial request rather than after quotation.

Step 2: Request a Complete Documentation Package

At minimum, I suggest requesting a current SDS, product specification, representative or lot-specific CoA, and packaging information. The CoA should identify the batch number, test date, test methods or references, results, and approval status where applicable. For repeat procurement, also request information about retest policy, shelf-life basis, storage conditions, and notification of significant specification or manufacturing changes.

Step 3: Compare Commercial Conditions

Price should be compared together with net quantity, assay basis, packaging, freight terms, lead time, and documentation support. A quotation for 100 g may not be directly comparable with a quotation for the same nominal quantity if the products have different assay limits or testing packages. Ask whether the quoted price is for available stock, planned production, or a non-binding estimate.

Step 4: Confirm Sample and Scale-Up Path

When the application is technically sensitive, request a small evaluation sample before committing to a larger order. The customer can then compare identity, assay, reaction performance, and handling behavior against internal standards. Before scale-up, confirm that the sample lot and commercial lot will follow the same specification and that any change in manufacturing source will be communicated.

Pricing, MOQ, and Lead-Time Questions

There is no single universal price or minimum order quantity for 4-isopropylbenzeneboronic acid because commercial terms vary by purity, pack size, inventory status, testing requirements, and destination. Buyers should ask for tiered pricing at practical quantities such as 1 g, 10 g, 100 g, and 1 kg when those quantities are relevant to the project. This creates a more useful comparison than requesting only one quantity.

Lead time should be stated as a number of business days or weeks and should distinguish ready stock from production lead time. I recommend asking whether the quoted lead time includes quality release, repacking, export documentation, and transportation. If a project requires delivery within 7 days, for example, the buyer should request written confirmation of stock status rather than relying on a general catalog indication.

Minimum order quantity may be influenced by the supplier’s standard packaging, production batch size, or special testing needs. If your requirement is below the standard MOQ, ask whether a smaller research pack is available or whether a consolidated shipment is possible. Maison Chemical can review the requested quantity, target specification, destination, and documentation needs to prepare a more relevant B2B quotation.

Supplier Evaluation Checklist

• Does the supplier clearly identify CAS 16152-51-5 and the intended chemical structure?
• Can the supplier provide a current SDS and specification sheet?
• Is a lot-specific CoA available before shipment or with the shipment?
• Are assay, moisture, residual solvents, and related impurities addressed where required?
• Is the quoted material available in the required pack size and quantity?
• Are lead time, MOQ, delivery terms, and packaging clearly stated?
• Can the supplier support sample evaluation and later scale-up?
• Does the supplier maintain batch traceability and communicate material changes?

Safety and transport decisions should be based on the current supplier SDS, applicable transport regulations, and the destination country’s requirements. The United Nations Globally Harmonized System of Classification and Labelling of Chemicals provides an authoritative framework for hazard communication, but the classification for a specific supplied product must be confirmed from its current SDS. I do not recommend assuming a hazard classification, storage temperature, or transport status from the chemical name alone.

Common Purchasing Mistakes

One common mistake is treating the catalog title as a complete specification. The name and CAS number establish an important identity reference, but they do not by themselves define assay, moisture, residual solvents, packaging, or lot release requirements. A second mistake is selecting the lowest unit price without checking whether the quoted grade and documentation match the actual application.

Another avoidable problem is failing to define the required delivery point and timeline. International shipments can involve export documents, customs review, repacking, and local transport, all of which may affect the final arrival date. I recommend confirming the shipping term, destination, package configuration, and required documents in writing before purchase order approval.

How Maison Chemical Can Support Your Sourcing Process

Maison Chemical supports B2B buyers evaluating organic boronic acids, including 4-isopropylbenzeneboronic acid CAS 16152-51-5. I can help organize the inquiry around product identity, target assay, quantity, pack size, application, destination, and documentation requirements. This approach allows our team to distinguish a standard quotation from a request that needs additional technical or quality review.

For repeat projects, I recommend discussing forecast quantities, preferred delivery frequency, acceptable alternative packaging, and the required document set at the beginning. Depending on the project, the purchasing package may include an SDS, specification sheet, CoA, packing information, and commercial export documents. Availability, MOQ, lead time, and exact testing scope should be confirmed for each quotation rather than assumed.

Key Takeaways

• 4-Isopropylbenzeneboronic acid is commonly identified as CAS 16152-51-5 with an approximate molecular weight of 164.01 g/mol.
• It is primarily evaluated as an aryl boronic acid building block for synthetic chemistry and coupling-related research.
• Buyers should confirm identity, assay, moisture, impurities, physical form, packaging, and lot traceability.
• A current SDS, specification sheet, and CoA are central documents for responsible supplier evaluation.
• Price comparisons should include quantity, grade, testing, MOQ, lead time, delivery terms, and documentation.
• For scale-up or regulated development, sample approval and change-control expectations should be agreed in advance.

Conclusion: How to Make the Next Purchasing Decision

The best way to buy 4-isopropylbenzeneboronic acid CAS 16152-51-5 is to treat it as a documented chemical supply requirement rather than a simple catalog purchase. First define your application and acceptance criteria, then compare suppliers using current technical documents, batch information, commercial terms, and supply continuity. This process reduces the risk of receiving a material that is chemically identified but not suitable for your specific reaction or quality system.

As your next step, prepare the required quantity, target assay, application stage, destination, preferred delivery date, and document list. Send these details to Maison Chemical for availability, MOQ, lead-time, packaging, and quotation review. I can then help you determine whether a standard research-grade supply or a more controlled, project-specific specification is the better fit.

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